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phenobarbital will minimize the level or outcome of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers may possibly reduce partiaprevir and ritonavir levels, and thus decreased efficacy of Viekira PakContraindicated (1)phenobarbital decreases levels o